Molecular Tumour Board
Complex cases deserve structured discussion.
Some questions need clinical history, pathology, imaging, molecular findings and prior treatment considered in the same conversation. KPCIRC’s MTB pathway supports multidisciplinary review of selected cases where additional perspectives may help organise the evidence and clarify what remains uncertain.
The aim of multidisciplinary review is to bring the available clinical history, pathology, molecular reports and treatment context into one defined process, and to document the relevant considerations and unresolved questions for the treating clinician.
Cases that may be considered
Reports to read together
Complex clinical questions for which several reports need to be considered at once.
Evidence questions
A molecular report that raises therapeutic, biomarker or evidence-strength questions.
Progression
A change in disease status that raises new questions about the disease or prior therapy.
Discordant information
Discordant or incomplete information across pathology, imaging, clinical and molecular records.
Structuring next questions
A need to structure questions for possible further testing, trial review or another clinical discussion.
Submitting a case does not guarantee acceptance, a particular recommendation or access to a specific treatment or trial. Suitability depends on the information supplied, the question, available expertise and the agreed scope.
Information to prepare
- The primary diagnosis, histology and available pathology reports.
- Disease stage and relevant imaging or radiology summaries.
- Prior and current systemic therapies, with dates where known, and documented response or progression.
- Relevant NGS, molecular, biomarker and pathology reports.
- Key clinical factors, including comorbidities and current clinical status where relevant.
- A concise statement of the clinical question to be discussed.
- Contact details for the referring or treating clinician, and patient authorisation or consent where required.
Records are shared only through the approved secure route after intake, never through a general contact form.
How a review is organised
Intake
The submission is checked for required material and a clear clinical question.
Triage
The case is assessed for suitability and whether further information is needed.
Preparation
Clinical, pathological, molecular and treatment context is organised for discussion.
Multidisciplinary discussion
Selected cases are reviewed within the available expertise and agreed scope.
Documentation
Considerations, evidence limitations, missing information and questions are recorded.
Clinical follow-through
The treating clinician interprets the review in the context of the full record and retains responsibility.
What the requesting clinician receives
Case summary
A structured summary of the submitted case and its principal question.
Organised context
An organised review of the available clinical and molecular context.
Considerations
Relevant considerations and evidence limitations within the agreed scope.
Open questions
Questions or information gaps that may merit further assessment.
Documented output
A documented review output according to the service workflow.
Clinical governance
An MTB review supports, but does not replace, the treating clinician’s judgement. The quality and usefulness of a review depend on the completeness and accuracy of the information supplied, and a board discussion cannot guarantee a particular clinical outcome. Responsibilities for intake, review, sign-off and communication are defined in the service agreement.
Frequently asked questions
Does every case need an MTB?
No. Some questions are suitable for a report interpretation or an individual consultation; others may merit multidisciplinary discussion. KPCIRC can assess the most suitable pathway from the submitted question and records.
Must the patient be physically present?
The format of each review, including whether it is case-based and how the treating clinician participates, is confirmed when the request is accepted.
Does the MTB issue prescriptions?
No. The MTB pathway documents review considerations. Treatment decisions and prescribing remain with the responsible treating clinician, subject to the service arrangement and professional requirements.
Short explainers, in production
- How an MTB review worksAbout 60–90 seconds
Enquiry
Request an MTB review
Tell us about the type of case and question. Records are requested later through the approved secure route, only if the case is suitable.
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- This form is not for emergencies or medical records.
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Enquiry received
Thank you. Your MTB request has been received. Intake will check the question and required material, then explain whether the case is suitable and what is needed. Receipt does not confirm acceptance.
Illustrative scenarios
Educational composite scenarios that explain possible workflows. They are not real KPCIRC patients, testimonials or outcomes.